ANALYSIS OF ACTIVITY OF EXISTENT ANTIMICROBIAL PREPARATIONS ON MARKETS OF UKRAINE

A. Golovko, G. Dmytryyeva, N. Pinchuk

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State Scientific Control Institute of Biotechnology and strains of microorganisms,
st. Donetska, 30, Kyiv, 03151, Ukraine

In the article are expounded results of researches of sensitiveness of neat cultures of tests are to the wide spectrum of antimicrobial preparations, with the purpose of determination of their activity. The analysis of activity of antibiotics which are used in veterinary medicine is conducted, in accordance with standard standards, with the purpose of determination of the falsifyed preparations. The results of activity of benzilpenicilinu of different producers are resulted with the purpose of comparison of findings of not below of possible minimum indexes of activity. Analysis of international and domestic bases of these collections of cultures of tests, enabled to take away highly sensitive microorganisms for determination of activity of antimicrobial preparations. To carry out a selection, preliminary studying characteristic properties of cultures and their sensitiveness to the wide spectrum of antibiotics. By a disko-diffusion method and diffusion in an agar the results of researches are got in relation to the study of sensitiveness of cultures of tests of microorganisms to the different antimicrobial matters and the set of cultures of tests is formed for determination of activity of antibiotics by a microbiological method. From the results of researches the table of sensitiveness of cultures of tests is resulted to the minimum concentrations of basic standards of antibiotics of different groups, dividing into every culture which enables to compare the got results of the probed preparations on accordance of their activity of indicated in instruction of application.

For today modern methods of determination of activity of antibiotics are practically inaccessible for the state laboratories of veterinary medicine of Ukraine, as need dear equipment and highly skilled specialists for the leadthrough of researches on him. Simple enough and by fasts in application, relatively inexpensive, highly sensitive and accessible for the state laboratories of veterinary medicine there are biological methods of control of quality of medical preparations.

Keywords: ACTIVITY, ANTIMICROBIAL PREPARATIONS, CULTURES OF TESTS, ANTIBIOTICS

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