THE INDICES OF ANTIOXIDANT DEFENSE SYSTEM IN PIGLETS UNDER FERUM CITRATE ACTION

R. Z. Berezovskiy, I. Ya. Maksymovych, V. V. Vlizlo

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Institute of Animal Biology NAAS,
38 V. Stus St, Lviv, 79034, Ukraine

The data about the indices of antioxidant defense system in piglets after intramuscular injection the different doses of ferum citrate (100 ml of solution contains 0.4 mg Fe) for the ferum deficiency anemia prophylaxis were presented in the paper. Ferum citrate was prepared on the nanotechnology foundation.

For experiment the control and four research groups of newborn suckling piglets of Landras breed were used. The control piglets were injected 1.5–2.0 ml/per head the traditional ferum contained preparation of Bioferon (100 ml of solution contains 100 mg Fe) for the ferum deficiency anemia prophylaxis. The experimental piglets were injected ferum citrate in the doses of 2.0 mg/per head, 1.5 mg/per head, 1.0 mg/per head, 0.5 mg/per head. The experiment lasted 32 days.

The obtained results shown that ferum citrate promotes the increasing of superoxide dismutase, catalase, glutathione peroxidase activity and reduced glutathione. The finest effect on the enzymes chain of antioxidant defense of suckling piglets was observed in the experimental animals which were injected 1.5 mg ferum citrate/per head on the 2 days after birth for the ferum deficiency anemia prophylaxis. Ferum citrate provides the higher biological availability of ferum for the new erythrocytes formation in the piglet’s organism.

Keywords: PIGLETS, FERUM DEFICIENCY ANEMIA, BLOOD, FERUM, CITRATE, BIOFERON, SUPEROXIDE DISMUTASE, CATALASE, GLUTATHIONE PEROXIDASE, REDUCED GLUTATHIONE

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