EFFECT OF ENDOTOXICOSIS ON THE MORPHOLOGICAL AND BIOCHEMICAL BLOOD INDICES OF PREGNANT COWS

Y. I. Grymak

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Lviv National University of Veterinary Medicine and Biotechnology named after S. Z. Gzhytsky,
50 Pekarska str.
, Lviv 79010, Ukraine

The research findings about the influence of endotoxicosis in cows on morphological and biochemical blood indicators are showed in the article. It is found that the development of endotoxicosis in pregnant cows is accompanied by decreased red blood cell count, hemoglobin level, total protein, increased activity of aminotransferases and increased number of white blood cells in blood compared with the value of these indicators in the blood of cows with a physiological course of pregnancy. The development of endotoxicosis in pregnant cows also contributes to the violation of protein and bilirubinsynthesiz, detoxifying functions of hepatocytes and the disruption of a kidney filtration function.

The cows with the signs of endotoxicosisshowed lower content of total protein compared with the control group of cows, and also were reported to show decreased content of albumin during the 8thand 9th months of pregnancy. The study of globulin fractions in the blood of the cows of the experimental group during the 8th month of pregnancy showed the increase of α — and β-globulins by 16 and 15 % in comparison to the values of the control group. A low level of urea in blood of the cows of the experimental group, the values of which decreased by 15 and 31 % during the 8th and 9th months of pregnancy respectively, compared to the control animals, indicates the decrease of detoxification function of the liver.

Key words: COWS, ENDOTOXICOSIS, BLOOD, PREGNANCY, PROTEIN, HEMOGLOBIN, AMINOTRANSFERASES

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