Bìol. Tvarin, 2016, volume 18, issue 4, pp. 30–34                                        http://dx.doi.org/10.15407/animbiol18.04.030

PECULIARITIES OF MORPHOGENESIS OF UNIVERSAL HEMATOPOESIS AND IMMUNE PROTECTION IN FETUSES OF DOMESTIC PIG

P. Gavrilin, A. Oliyar, O. Myrnyi

This email address is being protected from spambots. You need JavaScript enabled to view it.

Dnipropetrovsk State Agrarian and Economic University,
25
Voroshylova, str., Dnipro 49600, Ukraine

It was established that prenatal skeletal ontogeny in domestic pigs is presented in two forms: structural and functional bone marrow osteoblast (bone formation) and hematopoietic (blood-forming) development and structural and functional transformation that is taking place in parallel, different speeds towards vectors which are in particular histogram and cytoarchitectonic in different zonal centers of ossification of the skeleton in the fetus. The main structural components of the bone marrow domestic pig fetal within cells of the bone marrow centers of ossification of the bone shaft located in some models directly related to the dynamics of quantitative tissue components.

In the fetuses of especially late in the fetal period of ontogenesis (from 3 months) against the background of almost complete disappearance of hematopoietic centers in the liver begin to form as an unfinished structure segments with indistinct borders and lobules, although expressive (Relief) with outline radial hepatocyte structure and separated from each other with a thick connective tissue.

The basic characteristics, structural and functional bone marrow of the domestic pig fetuses are: localization in the spongy bone, leading to skeletal ossification centers, clearly marked morphological heterogeneity of the osteogenic distribution peripheral and central — hematopoietic form. Zonal structure of hematopoietic marrow gives the presence of islets and islet diffuse, with topographically distinct sections.

Keywords: LIVER, BONE MARROW, FETAL DOMESTIC PIG, OSSIFICATION CENTERS

1. Alison M. R., Poulsom R., Forbes S. J. Update on hepatic stem cells. Liver, 2001, 21 (6), pp. 367–373. https://doi.org/10.1034/j.1600-0676.2001.210601.x
2. Allen T. D. Haemopoietic microenvironments in vitro: ultrastructural aspects. Microenvironments in haemopoietic and lymphoid differentiation, 1981, pp. 38–67.
3. Chai B., Tang X., Li H. Osteoclastic resorbtion of Haversian systems in cortical bone of femoral neck in aged women. A scanning electron microscopic study. Chinese Medical Journal, 1996, vol. 109, no. 9, pp. 705–710.
4. Michurina T. V., Khrushchov N. G. Experimental analysis of cell interactions during haemopoiesis. Int. Journal Dev. Biol., 1997, vol. 41, pp. 817–833. (in Russian)
5. Michurina T., Krasnov P., Balaz A., Nakaya N., Vasilieva T., Kuzin B., Khrushchov N. Nitric oxide is a regulator of hematopoietic stem cell activity. Mol. Therapy, 2004, vol. 10, no. 2, pp. 241–248. (in Russian) https://doi.org/10.1016/j.ymthe.2004.05.030
6. Myrnyi O., Oliyar A. Morphogenesis haematopoietic components of the universal haematogenesis and immune protection of domestic pig’s fetuses. Sciense and Technology Bulletin of Scientific research center for biosafety and environmental control of agro-industrial complex, 2014, vol. 2, no. 1, pp. 37–43. (in Ukrainian)
7. Parkman R. The biology of bone marrow transplantation for severe combined immunodeficiency. Adv. Immunol., 1991, vol. 49, pp. 381–388. https://doi.org/10.1016/S0065-2776(08)60780-4
8. Peck W. A. Bone and mineral research. Amsterdam New York — Oxford: Elserier, 1989, pp. 338–410.
9. Taylor D., Dharmar M, Urquhart-Scott E, Ryan R. Relationship between pediatric blood and marrow transplant center volume and day +100 mortality: Pediatric Blood and Marrow Transplant Consortium experience. Bone Marrow Transplant, 2013, pp. 14–22. https://doi.org/10.1038/bmt.2012.192
10. Weiss L. The structure of bone marrow. Functional interrelation ships of vascular and hematopoietic compartments. An in experimental hemolytic anemia. An electron microscopic study. Journal Morphol., 1965, vol. 117, no. 3, pp. 467–537. https://doi.org/10.1002/jmor.1051170308

Download full text in PDF format

© 2016 Institute of Animal Biology

Search