INDICATORS OF BIOPOLYMERS OF CONNECTIVE TISSUE IN THE BLOOD SERUM OF HORSES OF DIFFERENT PHYSIOLOGAL GROUPS

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Bìol. Tvarin, 2015, volume 17, issue 3, pp. 52–56

INDICATORS OF BIOPOLYMERS OF CONNECTIVE TISSUE IN THE BLOOD SERUM OF HORSES OF DIFFERENT PHYSIOLOGAL GROUPS

M. I. Kartashov, O. P. Timoshenko, D. V. Kibkalo, K. B. Skripova

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Kharkiv state Zooveterinary Academy,
p/o Malaya Danilovka, Dergachovsky district, Kharkov region, 62341, Ukraine

A comparative analysis of the indicators of biopolymers of connective tissue in the blood serum of healthy foals of all ages, brood-mares and stallions had been conducted. According to the results of clinical research four groups of animals were formed: I group — foals of age 4–6 months, group II — foals of age 1–1.5 years, group III — brood-mares and group IV — stallions.

The blood of these animals was taken to obtain blood serum and its subsequent biochemical analysis. In the blood serum a total protein, cholesterol, urea, creatinine, activity of AST and activity of indicators of biopolymer content in the connective tissue in blood serum, general chondroitinsulfate and glycosaminoglycans fractions were determined.

It has been established significantly that foals aged 4–6 months have higher at 54 % content of total chondroitin (0,17±0,016 g/l). The lowest level of chondroitin was detected in stallions (0,079±0,004 g/l). The level of I fraction GAG — chondroitin-6-sulfate was the same in all groups. The level of II fraction GAG — chondroitin-4-sulfate was significantly lower in foals of age 1–1.5 years. Content of III GAG fractions which contains component of basement membranes in parenchymatous organs heparan sulfate, in foals serum regardless of age was higher than in mares and stallions (P<0.01).

The content of chondroitin sulfates and individual fractions of GAGs in the serum of horses of different age and sex shows the degree of catabolism and synthetic reactions in skeletal tissue and basal membranes of parenchymal organs that occur intensively in foals of age 2–6 months.

Keywords: HORSE, AGE, BLOOD SERUM, BIOCHEMICAL RESEARCHES, CHONDROITINSULFATE, FACTIONS OF GLYCOSAMINOGLYCANS

1. Kartashov M. I., Tumoshenko O. P., Kidkalo D. V. Use of connective tissue indexes in diagnostic of internal noninfectious diseases in animals. Scientific bulletin of Bilocerkivskyi DAY, 2006, vol. 40, pp. 68–75. (in Ukrainian)

2. Ferlazzo A., Campo S., Vinci R. Concentration and composition of serum and plasma glycosaminoglycans in domestic animal species. Comparative-Biochemistry-and-Physiology. English, 2004, 118, pp. 935–942.

3. Panchaphanpong J., Asawakarn T., Pusoonthornthum R. Effects of oral administration of N-acetyl-D- glucosamine on plasma and urine concentrations of glycosaminoglycans in cats with idiopathic cystitis. The American Journal of Veterinary Research (AJVR), 2011, 72 (6), pp. 843–850.

4. Mopozenko D. V. biochemical indexes of metabolism of connective tissue in diagnostics of diseases of small domestic animals. Kharkiv, 2011, 120 p. (in Ukrainian)

5. Ctrelnikova N. O., Kraevckiu A. U. Connective tissue exhange during critical periods of pregnancy. Scientific bulletin Lugansk NAY. 2011, no. 31, pp. 188–190. (in Ukrainian)

6. Kidkalo D. V. contents of biopolimers Inde of connective tissue in serum blood in cows of different physiology groups. collection of proceedings Kharkiv DZVA, 2010, vol. 138 (3), pp. 220–224. (in Ukrainian)

7. Levhenko V. I., Golovaxa V. I., Kondraxin I. P. Rublenko M. V, Cahnuk V. V. methods of laboratory clinical diagnostics of diseases of animals. Kyiv, Agrarian education, 2010, 437 p. (in Ukrainian)

8. Kidkalo D. V. Contents of bindweed status indicators in the serum from clinically healthy animals. Vestnik veterenarii, 2013, no. 64, pp. 33–35. (in Russian)

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