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THE INFLUENCE OF «MEVESEL» ON THE LEVEL OF NON-ENZYMATIC OF ANTIOXIDANT SYSTEM PROTECTING OF THE YOUNG BULLS ORGANISM UNDER THE INFLUENCE OF CADMIUM LOADING

B. V. Hutiy

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Lviv National University of Veterinary Medicine and Biotechnologies

named after S. Z.Gzhytskyj, 79010, Lviv, Pekarska str., 50

The article presents the results of search data under the infuense of cadmium chloride on the performance of indicators of non-enzymatis system of antioxidant defense in young cattle. It was found out that when fed young bulls with toxicant at a dose of 0.04 mg/kg of animal body weight the level of reduced glutathione, selenium, vitamin A and E levels in experimental calves throughout the experiment was decreased. The lowest indices of antioxidant system that was investigated, it was found on the twenty-fourth day of the experiment. In the conditions of cadmium load of young cattle it was used a new integrated drug with antioxidant action «Mevesel», which is composed of sodium selenite, vitamin E and methionine. We found the stimulating effect of the drug on the activity of antioxidant protection. In particular it was determined the reliable increase of level in reduced glutathione, selenium, vitamin A and vitamin E in the blood of young cattle, which carried cadmium loading. These changes are due to complex action of components of the drug, that leads to normalization of metabolic and free radical processes in the bulls organism. The results of the study indicate antioxidant action of «Mevesel» at feeding its young cattle and the validity of its input to improve the antioxidant status of the organism in cadmium loading.

Keywords: TOXICOLOGY, BULLS, ANTIOXIDANT SYSTEM, LIPID PEROXIDATION, MEVESEL, SELENIUM, REDUCED GLUTATHIONE, VITAMIN E, AND VITAMIN A


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