Bìol. Tvarin, 2015, volume 17, issue 3, pp. 52–56

INDICATORS OF BIOPOLYMERS OF CONNECTIVE TISSUE IN THE BLOOD SERUM OF HORSES OF DIFFERENT PHYSIOLOGAL GROUPS

MIKartashov, OPTimoshenko, DVKibkalo, K. B. Skripova

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Kharkiv state Zooveterinary Academy,
p/o Malaya Danilovka, Dergachovsky district, Kharkov region, 62341, Ukraine

A comparative analysis of the indicators of biopolymers of connective tissue in the blood serum of healthy foals of all ages, brood-mares and stallions had been conducted. According to the results of clinical research four groups of animals were formed: I group foals of age 46 months, group II foals of age 11.5 years, group III brood-mares and group IV stallions.

The blood of these animals was taken to obtain blood serum and its subsequent biochemical analysis. In the blood serum a total protein, cholesterol, urea, creatinine, activity of AST and activity of indicators of biopolymer content in the connective tissue in blood serum, general chondroitinsulfate and glycosaminoglycans fractions were determined.

It has been established significantly that foals aged 46 months have higher at 54 % content of total chondroitin (0,17±0,016 g/l). The lowest level of chondroitin was detected in stallions (0,079±0,004 g/l). The level of I fraction GAG chondroitin-6-sulfate was the same in all groups. The level of II fraction GAG  chondroitin-4-sulfate was significantly lower in foals of age 11.5 years. Content of III GAG fractions which contains component of basement membranes in parenchymatous organs heparan sulfate, in foals serum regardless of age was higher than in mares and stallions (P<0.01).

The content of chondroitin sulfates and individual fractions of GAGs in the serum of horses of different age and sex shows the degree of catabolism and synthetic reactions in skeletal tissue and basal membranes of parenchymal organs that occur intensively in foals of age 26 months.

Keywords: HORSE, AGE, BLOOD SERUM, BIOCHEMICAL RESEARCHES, CHONDROITINSULFATE, FACTIONS OF GLYCOSAMINOGLYCANS

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