Bìol. Tvarin, 2018, volume 20, issue 4, pp. 55–60


Yu. O. Sisyuk, Yu. V. Kravchenko-Dovga, V. I. Karpovsky, O. V. Danchuk, O. V. Zhurenko

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National University of Life and Environmental Sciences of Ukraine,
15 Geroyiv Oborony str., Kyiv 03041, This email address is being protected from spambots. You need JavaScript enabled to view it.

New scientific data concerning the degree and nature of the influence of the main characteristics of cortical processes on the activity of superoxide dismutase and the content of Copper and Zinc in the blood of cows are presented. The experiment has been conducted on cows of Ukrainian black-and-white breed of 2nd–3rd lactation with different types of higher nervous activity (HNA). Investigations of conditioned-reflex activity were performed according to the modified method of conditional-food reflexes G. V. Parshutina and T. V. Hippolyte. The research material used was blood samples of animals that determined the content of Zinc and Copper and the activity of superoxide dismutase.

It has been found that in cows of strong, balanced inert and strong unbalanced type of HNA, the content of zinc in the blood was lower by 17.1 % (P<0.001) and 18.5 % (P<0.01) in accordance with indicators of strong, balanced, mobile type cows, whereas, as the contents of Copper did not differ significantly. In animals of the weak type of GNI, the content of zinc and Copper in the blood is significantly less than 8.3 % (P<0.05) and 24.6 % (P<0.001), respectively, of the animals of a strong, well-balanced, type of animal. The activity of superoxide dismutase in the blood of cows of a strong, balanced, mobile and strong, balanced inert type of HNA does not differ significantly and rises above 17.2–24.1 % (P<0.05) from the indicator of strong and unbalanced and weak type animals. The strength of the cortical processes affects the content of Copper, Zinc and the activity of superoxide dismutase in the blood of cows (P<0.01–0.05). Correlation of cortical processes significantly limits the activity of superoxide dismutase and the content of zinc in the blood (P<0.01), and the mobility of excitatory and inhibition processes in the cerebral cortex affects only the content of zinc in the blood of cows (P<0.01).


  1. Andrewartha K. A., Caple I. W. Effects of changes in nutritional copper on erythrocyte superoxide dismutase activity in sheep. Research in Veterinary Science, 1980, vol. 28, issue 1, pp. 101–104. https://doi.org/10.1016/S0034-5288(18)32781-4
  2. Bowler C., Montagu M., Inze D. Superoxide dismutase and stress tolerance. Annual review of plant biology, 1992, vol. 43, pp. 83–116. https://doi.org/10.1146/annurev.pp.43.060192.000503
  3. Danchuk O. V., Karpovskyi V. I., Trokoz V. O., Postoi R. V. Regulation mechanisms of cortisol level in pigs’ blood serum under stress. Physiological. Journal, 2017, vol. 63, no. 6, pp. 60–65. (in Ukrainian) https://doi.org/10.15407/fz63.06.060
  4. Danchuk V. V. Processes of lipid peroxidation, hormonal and substrate mechanisms of regulation of antioxidant system in pig tissues. A dissertation. Lviv, Institute of Animal Biology UAAS, 2002, pp. 290. (in Ukrainian)
  5. Danchuk V. V., Danchuk A. V., Tsepko N. L. Oxidative stress — is it a pathology or an adaptation? Livestock of Ukraine, 2004, no. 4, pp. 21–23. (in Ukrainian).
  6. Deng H. X. Hentati A., Tainer J. A., Iqbal Z., Cayabyab A., Hung W. Y., Getzoff E. D., Hu P., Herzfeldt B., Roos R. P. Amyotropic lateral sclerosis and structural defects in Cu, Zn superoxide dismutase. Science, 1993, vol. 261, issue 5124, pp. 1047–1051. https://doi.org/10.1126/science.8351519
  7. Institute of Medicine. Dietary reference intakes for vitamins and minerals. National Academy Press, Washington, DC, 2000.
  8. Karpovskyi P. V., Karpovskyi V. V., Trokoz A. V., Landsman A. A., Skrypkina V. N., Postoi R. V., Kryvoruchko D. I., Trokoz V. O., Karpovskyi V. I. Cortico-vegetative regulation of relations in the physiological functions of pigs. The Animal Biology, 2015, vol. 17, no. 2, pp. 65–73. (in Ukrainian)
  9. Karpovskyi V. I., Trokoz V. O., Danchuk O. V., Postoi R. V., Karpovskyi V. V., Vasyliv A. P. The influence of the main cortical processes on the productivity of pigs during the period of technological stress. Ecology and animal world, 2016, no. 2, pp. 8–13. (in Ukrainian)
  10. Kokorina E. P. Conditioned reflexes and productivity of animals. Moscow, Agropromizdat, 1986, 335 p. (in Russian)
  11. Marklund S., Marklund G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. The FEBS Journal, 1974, vol. 47, no. 3, pp. 469–474.
  12. McDowell L. R. Minerals in animal and human nutrition. 2nd ed. Elsevier Health Sciences, 2003, 644 p.
  13. Naumenko V. V. Some features of higher nervous activity and types of the nervous system in pigs. A dissertation abstract. Lviv, LNUVM named after S. Z. Gzhytsky, 1968, 36 p. (in Ukrainian)
  14. Parshutin G. V., Ippolitova T. V. Types of higher nervous activity, their definition and relationship with the productive qualities of animals. Frunze, Kyrgyzstan, 1973. (in Russian)
  15. Spears J. Trace mineral bioavailability in ruminants. The Journal of Nutrition, 2003, vol. 133, issue 5, pp. 1506S–1509S. https://doi.org/10.1093/jn/133.5.1506S
  16. Underwood E. J., Suttle N. F. The Mineral Nutrition of Livestock. 3rd ed. Oxon, CABI Publishing; 1999, 614 p. https://doi.org/10.1079/9780851991283.0000
  17. Vlizlo V. V. (ed.), Fedoruk R. S., Ratych I. B. Laboratory methods of research in biology, animal husbandry and veterinary medicine. A guide. Lviv, Spolom, 2012, 764 p. (in Ukrainian)
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