Bìol. Tvarin, 2016, Volume 18, Issue 2, pp. 80–87

http://dx.doi.org/10.15407/animbiol18.02.080

CLASSIFICATION AND ETIOLOGY OF CARDIOMYOPATHY IN DOMESTIC CATS: CLINICAL CASE OF INTERMEDIATE FORMS OF CARDIOMYOPATHY

V. N. Plysiuk1,2, M. I. Tsvilikhovski1

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1NationalUniversity of Life andEnvironmental Sciences of Ukraine,
15 Heroiv Oborony str., Kyiv 03041, Ukraine

2Network veterinary clinics VC «Alden-Vet»,
34 M. Malinowski
str., 10А V. Lobanovsky pr., Kyiv, Ukraine

The article presents the current view on the classification and causes of cardiomyopathy in cats. Currently, a large number of cases of clinical manifestation of cardiomyopathy can not be displayed in existing classification. If carefully considered by the division of cardiomyopathies etiological factor, they are divided into primary (idiopathic) and secondary (etiological factor set).

The primary cardiomyopathies are: hypertrophic (asymmetric and symmetric, obstructive and nonobstructive), dilated (or stagnant), restrictive (obliterans and diffuse) and intermediate. The secondary cardiomyopathies include: metabolic (endocrine, nutritional origin); infiltrative (neoplastic processes); inflammatory (immunomediated, coronaviral infection, immunodeficient virus); fibrous (postinfectious); toxic (application doxorubicin, cyclophosphamide); other (chronic renal failure, trauma, heart attack).

Cardiomyopathies in cats may show one or more of the grounds which can be used to divide them into different forms. In such cases, one can observe the intermediate phase of the disease, the development of which leads to the final phase of myocardial damage which is easier to subject classification.

In many cases, at the first survey of cats with suspected cardiomyopathy echocardiography method can not immediately classify intermediate or another form of cardiomyopathy. It is necessary to hold 2–3 and sometimes more ultrasound examinations of the heart with an interval 4–6 months and apply clinical and laboratory diagnostic techniques of cats with suspected cardiomyopathy to exclude the presence of secondary forms of cardiomyopathy.

Unfortunately, each classification schemes are incomplete and some cases may be undetected cardiomyopathy, and others will be difficult to attribute to a specific form. Although these forms of cardiomyopathey have no clearly defined boundaries, divide them into hypertrophic, restrictive and dilated is clinically significant.

Keywords:MYOCARDIUM, CARDIOMYOPATHY, ETIOLOGY, CLASSIFICATION, ECHOCARDIOGRAPHY

1. Goodwin J. F. The frontiers of cardiomyopathy. British Heart Journal, 1982, vol. 48, pp. 1–18. https://doi.org/10.1136/hrt.48.1.1
2. Amosova K. M. Cardiomyopathy. Kyiv, Book plus, 1999, 213 p. (in Ukrainian)
3. Fox P. R. Feline myocardial diseanse. Canine and Feline Cardiology, Churchill Livingstone, New York, 1988, pp. 435–466.
4. Ivkina S. S., Bubnevich T. E., Kravchuk Zh. P., Rumyantseva O. A. Cardiomyopathy in children: literature review. Health and environmental problems, 2012, no 3, pp. 22–28. (in Belorussian)
5. Storozchakov G. I. Cardiomyopathies: Evolutions of Views of the Problem. Medical business. 2009, no 1, pp. 3–12. (in Russian)
6. Shchedrina A. Yu., Skvortsov A. A., Zykov K. A., Safiullina A. A., Tereshchenko S. N. The role of parvovirus B19 in the development of inflammatory cardiomyopathy. Rational Pharmacotherapy in Cardiology, 2013, vol. 9 (5), pp. 542–550. (in Russian) https://doi.org/10.20996/1819-6446-2013-9-5-542-550
7. Maron B. J, Towbin J. A, Thiene G., Antzelevitch C., Corrado D., Arnett D., Moss A. J., Seidman C. E., Young J. B. Contemporary definitions and classification of the cardiomyopathies. Circulation, 2006, vol. 113, pp. 1807–1816. https://doi.org/10.1161/CIRCULATIONAHA.106.174287
8. Chandler E. A., Gaskell C. J., Gaskell R. M. Feline medicine and therapeutics. Moscow, Aquarium Print, 2011, 696 p. (in Russian)
9. Wingfield W. E. Veterinary emergency medicine secrets. Moscow, Publisher BINOM, Nevsky Dialect, 2000, 608 p. (in Russian)
10. Nanni L, Pieroni M, Chimenti C., Simionati B., Zimbello R., Maseri A., Frustaci A., Lanfranchi G. Hypertrophic cardiomyopathy: Two homozygous cases with «typical» hypertrophic cardiomyopathy and three new mutations in cases with progression to dilated cardiomyopathy. J. Biochem. Biophys. Res. Commun., 2003, vol. 309, no 2, pp. 391–398. https://doi.org/10.1016/j.bbrc.2003.08.014
11. Wawruch P. O. Histostereometric characteristics of antracycline cardiomyopathy and its correction. Journal of scientific Research, 2013, vol. 2, pp. 132–133. (in Ukrainian)
12. Fox P. R. Treatment of myocardial diseases in cats. Kirk’s current veterinary therapy. Small animal practice. Moscow, Aquarium Print, 2005, pp. 854–860. (in Russian)
13. Yin S. A. A comprehensive guide on veterinary medicine of small animals. Moscow, Aquarium Print, 2008, 1024 p. (in Russian)
14. Feldman E. C., Nelson R. W. Canine and feline endocrinology and reproduction medicine for small animals. Moscow, Sofion, 2008, 1256 p. (in Russian)
15. Frances Barr, Lorrie Gaschen. BSAVA Manual of Canine and Feline Ultrasjnjgraphy. A Company Limited by Guarantee in England, 2012, 222 p.
16. Plysiuk V. Regarding the etiology of cardiomyopathy cats. J. World veterinary, 2015, no. 6 (27), pp. 36–38. (in Ukrainian)
17. Horzinek M. C., Schmidt V., Lutz H. Praktika kliniczna: koty. Polskie widanie. Pro-Trade s.r.o. Bratislava, 2004, 868 p. (in Slovakian)
18. Wynne J., Braunwald E. The cardiomyopathies and myocarditides. In: Braunwald E. (ed). Heart Disease: A Textbook of Cardiovascular Medicine, 3rd ed. W. B. Saunders, Philadelphia, 1988, pp. 1410–1469.
19. Pion P. D., Kittleson M. D., Rogers Q. R. Cardiomiopathy in the cat and its relation to taurine deficiency. Current Veterinary Therapy X.W.B., Saunders, Philadelphia, 1989, pp. 251–262.
20. Kittleson M. D. Dilated cardiomyopathy in the American Cocker Spaniel caused by deficiency of taurine and carnitine. Kirk’s current veterinary therapy. Small animal practice., Moscow, Aquarium Print, 2005, pp. 853–854. (in Russian)
21. Koroleva E. B., Vostokova A. A. Peripartum cardiomyopathy. Diagnosis, prognosis, value for maternal mortality. Medical almanac, 2009, no 4 (9), pp. 82–86. (in Russian)
22. Keene B. W., Panciera D. P., Atkins C. E., Regitz V., Schmidt M. J., Shug A. L. Myocardial L-carnitine deficiency in a family of dogs with dilated cardiomyopathy. J. Am. Vet. Med. Ass., 1991, no. 198, pp. 647–650.
23. Rudebush P., Freeman L. M. Diet therapy for diseases of the heart. Kirk’s current veterinary therapy. Small animal practice. Moscow, Aquarium Print, 2005, pp. 798–803. (in Russian)
24. Meurs K. M., Sanchez X., David R. M., Bowles N. E., Towbin J. A., Reiser P. J., Kittleson J. A., Munro M. J., Dryburgh K., McDonald K. A., Kittleson M. D.. A cardiac myosin binding protein C mutation in the Maine Coon cat with familial hypertrophic cardiomyopathy. Oxford Journals Human Molecular Genetics, 2005, vol. 14, no 23, pp. 3587–3593. https://doi.org/10.1093/hmg/ddi386
25. Wess G., Schinner C., Weber K., Küchenhoff H., Hartmann K. Association of A31P and A74T polymorphisms in the myosin binding protein C3 gene and hypertrophic cardiomyopathy in Maine Coon and other breed cats. J. Vet. Intern. Med. 2010, no 24, pp. 527–532. https://doi.org/10.1111/j.1939-1676.2010.0514.x
26. Kresken J.-G. Katzenherzen. M. hundkatzepferd, 2010, vol. 3, pp. 6–8. (in German)
27. Rudenko K. V. Hypertrophic cardiomyopathy: analysis of immediate and long-term results of Staging Treatment. Bulletin problems of biology and medicine, 2013, vol. 4, no 1(104), pp. 203–208. (in Ukrainian)
28. Shaposhnik I. I., Bogdanov D. V. Differential diagnosis of hypertrophic cardiomyopathy and myocardial hypertrophy secondary origin. Russian Medical Journal. Cardiology, 2014, no 12, pp. 923–928. (in Russian)
29. Youschenko M. V., Shlyakhto E. V., Novik G. A., Kostareva A. A., Gudkova A. Ya. Clinical features of cardiomyopathies caused by cardiac troponin I mutations. Arterial hypertension, 2009, vol. 15, no 6, pp. 648–651. (in Russian)
30. Kostareva A., Gudkova A., Sjöberg G., Mörner S., Semernin E., Krutikov A., Shlyakhto E., Sejersen T. Deletion in TNNI3 gene is associated with restrictive cardiomyopathy. International J. of Cardiology, 2009, vol. 131, no 3, pp. 410–412. https://doi.org/10.1016/j.ijcard.2007.07.108
31. Seward J. B., Casaclang-Verzosa G. Infiltrative Cardiovascular Diseases: cardiomyopathy, which are difficult to differentiate. Rational Pharmacotherapy in Cardiology, 2010, vol. 6, no 5, pp. 722–732. (in Russian) https://doi.org/10.20996/1819-6446-2010-6-5-722-732

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